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Title	Pathak Lab \| University of California,
Description	top of page PATHAK LAB HOME LAB MEMBERS PUBLICATIONS WORK WITH US NEWS LAB LIFE DIVERSITY IN SCIENCE LINKS CONTACT US Mechano-regulation of neural stem ce
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pathaklab-uci.com Valuation

US$273,729

Last updated: 2023-05-15 09:01:17

pathaklab-uci.com has Semrush global rank of 38,667,171. pathaklab-uci.com has an estimated worth of US$ 273,729, based on its estimated Ads revenue. pathaklab-uci.com receives approximately 31,585 unique visitors each day. Its web server is located in -, with IP address 185.230.63.107. According to SiteAdvisor, pathaklab-uci.com is safe to visit.

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top of page PATHAK LAB HOME LAB MEMBERS PUBLICATIONS WORK WITH US NEWS LAB LIFE DIVERSITY IN SCIENCE LINKS CONTACT US Mechano-regulation of neural stem cells Piezo1 as a determinant of stem cell fate The long-term goal of our lab is to understand at molecular, cellular and organismal levels, how mechanical forces modulate neural stem cell fate in development and repair. We previously showed that the stretch-activated ion channel Piezo1 mediates mechanosensitive lineage specification of neural stem cells. Our studies revealed that Piezo1 activity in neural stem cells is modulated by matrix mechanics, and that it influences differentiation of the cells into neurons or astrocytes. Current work focuses on understanding (i) how Piezo1 detects and transduces matrix mechanical signals, (ii) how Piezo1 activity elicits gene expression changes, (iii) how Piezo1 may shape neural development, and (iv) how Piezo1 may be involved in certain disease states. We use a multi-disciplinary approach,

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pathaklab-uci.com valuation and analysis